Immune response of the harderian gland in chickens to infectious bronchitis coronavirus

نویسندگان

چکیده

Aim. To determine the difference in immune responses of harderian gland clinically healthy chickens and ones with infectious bronchitis based on content, localization morphometric estimation surface markers ?- ?-lymphocytes to differentiation index as an indicator assessing body defenses. Methods. Histological, immunohistochemical, optical, statistical. Results. The histological study determined swelling proliferation connective tissue well infiltration secretory lobules by lymphoid cells. It was found that immunity bronchitis, which plays a relevant role, depends considerably immunocompetent There reliable 1.77- 1.36-fold decrease this for 40- 90-day-old chickens, respectively, case nephroso-nephritic form demonstrated weaker function defense cells organ. According cytomorphometric analysis, number cells, expressing CD4+, CD8+, CD20+, CD45RA+ sick 20-, 40-, respiratory forms reliably (P < 0.05) increasing compared chickens. For instance, mature increased 20-day-old – 2.44 times, 40-day-old 1.88 2.62 times Conclusions. data were obtained about changes quantitative qualitative composition lymphocytes bronchitis. Our results will supplement current knowledge feasibility immunohistochemical methods diagnostics avian

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ژورنال

عنوان ژورنال: Agricultural science and practice

سال: 2021

ISSN: ['2312-3370', '2312-3389']

DOI: https://doi.org/10.15407/agrisp8.01.049